Searchable abstracts of presentations at key conferences in endocrinology

ea0047oc15 | Spotlight on Neuroendocrine tumours | Theranostics2016

Evaluation of somatostatin, CXCR4 chemokine and endothelin a receptor expression in a large series of paragangliomas

Kaemmerer Daniel , Saenger Joerg , Arsenic Ruza , D'Haese Jan G. , Neumann Jens , Singh Aviral , Baum Richard P. , Schulz Stefan , Lupp Amelie

Background: Paragangliomas are predominantly benign tumors, but in some cases invasive growth and also metastasis is observed. Given the limited number of nonsurgical treatment options, novel target structures for diagnostics and therapy of this tumor entity are urgently needed.Aims: In the present study the expression of the five somatostatin receptor (SSTR) subtypes as well as of the chemokine receptor CXCR4 and of the endothelin receptor A (ETA) was e...